EXPERIMENTAL DERMATOPHYTOSIS ON THE OUTER EAR OF GUINEA PIGS: A MODEL THAT MIMICS NATURAL INFECTION doi: http://dx.doi.org/10.5892/ruvrd.v12i1.1359

Raquel Oliveira FONTENELLE; Selene Maia de MORAIS; Erika Helena Salles de BRITO; Nilberto Robson Falcão do NASCIMENTO; José Telmo VALENÇA JÚNIOR; Marcos Fábio Gadelha ROCHA

doi:10.5892/ruvrd.v12i1.1359

EXPERIMENTAL DERMATOPHYTOSIS ON THE OUTER EAR OF GUINEA PIGS: A MODEL THAT MIMICS NATURAL INFECTION
doi: http://dx.doi.org/10.5892/ruvrd.v12i1.1359

Raquel Oliveira FONTENELLE, Selene Maia de MORAIS, Erika Helena Salles de BRITO, Nilberto Robson Falcão do NASCIMENTO, José Telmo VALENÇA JÚNIOR, Marcos Fábio Gadelha ROCHA

Resumo

In the present study a new model of experimental dermatophytosis was tested. The aim was to achieve maximum similarity to a natural infection through a procedure that is easy to carry out. The experimental infection was induced by a single inoculation of 0.5 mL of a suspension with hyphal fragments of T. mentagrophytes var. mentagrophytes on the outer ear of guinea pigs. The first signs of infection were observe on the seventh day after inoculation. The experiment demonstrated that this method, besides being effective, causes less stress and the clinical aspects the lesions here were similar to natural lesions.